antibody formation with ghk-cu Exploring the beneficial effects of on an experimental model of colitis and the underlying mechanisms Peptide GHK-CU Cream | Concierge

A 2023 phase II trial in 40 post-surgical patients found 0.5% GHK-Cu gel reduced scar volume by 35% at 3 months versus silicone (p=0.002) (Hosokawa et al., 2023)

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

Aqua, Methylpropanediol (hydration), Butylene Glycol (hydration), Polysorbate 20 (texture-enhancing), Salicylic Acid (Beta Hydroxy Acid, exfoliant), Phytosphingosine (skin-renewing), Hydroxyethylcellulose (texture-enhancing), Vitis Vinifera (Grape) Fruit Extract (antioxidant), Camellia Oleifera (Green Tea) Leaf Extract (antioxidant), Epilobium Angustifolium (Willow Herb) Flower/Leaf/Stem Extract (skin-soothing), Bisabolol (skin-soothing), Tetrasodium EDTA (stabilizer), Sodium Hydroxide (pH adjuster)

Copper delivery and enzyme support Copper ions act as cofactors for enzymes involved in Cross linking of collagen and elastin Redox reactions and antioxidant defense Other steps in tissue maintenance and repair By binding copper, the GHK tripeptide appears to present copper to cells in a controlled way in experimental systems, which may help explain some of the observed effects

Activation of autophagy, observed in liver tissues from patients with Wilson disease and from atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis

mechanism matters